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Welcome to PHIDIAS!

 

PHIDIAS is a web-based database and analysis system that aims to manually curate, computationally analyze, and address different scientific issues in the areas of pathogen-host interactions (PHI, or called host-pathogen interactions or HPI). PHIDIAS has emphasized the study of those pathogens that cause various infectious diseases in humans and animals.

Some key features about PHIDIAS:

We have generated a manually curated database, which is called Victors, to store and analyze various virulence factors from different pathogens that infect humans and animals. The Victors data has now been utilized by different groups and projects, including the PATRIC Specialty Genes resource.

PHIDIAS was initially generated by expanding our internally developed Brucella Bioinformatics Portal (BBP). BBP is a valuable resource and portal for Brucella researchers around the world.

As reported in the original PHIDIAS paper, PHIDIAS collects and analyzes valuable information related to PHI in different aspects, such as general PHI information (Phinfo), PHI network information annotation (Phinet), and biohazard information (HazARD).

Another ongoing PHIDIAS research focus is to explore how ontologies can be used to better represent and integrate PHI data. For example, we have developed a Brucellosis Ontology (IDOBRU) to represent Brucella and brucellosis-related terms and the relations among these terms. Such an ontology can be used as a knowledge base to support data integration and advanced data analysis.


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© 2007-2022 University of Michigan. PHIDIAS data and tools are freely available for public use.