Protegen ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Protein Annotation Molecule Role Molecule Role Annotation COG PMID 4485 NS2A Yellow fever virus 1890270 nonstructural protein NS2A Virulence factor MUTATION: A mutation in the cleavage site in NS2A resulted in a block in the production of infectious virus [Ref7022:Kümmerer and Rice, 2002].; 11967294 4486 E Yellow fever virus 9558716 envelope protein Virulence factor MUTATION: E protein mutations in the 17D strain led to mortality and morbidity in mice defective in both type I and type II interferon responses [Ref7023:McArthur et al., 2005].; . 15845256 4487 NS3 Yellow fever virus 27735293 non-structural protein NS3 Virulence factor MUTATION: NS3 mutant results in failure to recover infectious virus from transfected mammalian cells [Ref7024:Chambers et al., 1990].; 2147282 4488 prM Yellow fever virus 222778 precursor polyprotein Virulence factor MUTATION: A mutation in the prM signal sequence led to attenuation in the neurovirulence in mice [Ref7025:Lee et al., 2000].; 10590087