Protegen ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Protein Annotation Molecule Role Molecule Role Annotation COG PMID 1964 virG from Burkholderia mallei NCTC 10229 Burkholderia mallei NCTC 10229 4789543 124382415 BMA10229_0713 YP_001024528.1 DNA-binding response regulator Virulence factor MUTATION: virG mutant is avirulent in hamsters [Ref6614:Nierman et al., 2004]. COG0745TK, under T: Signal transduction mechanisms; K: Transcription 15377793 1975 virG from Burkholderia mallei NCTC 10247 Burkholderia mallei NCTC 10247 4890091 126447328 BMA10247_A1669 YP_001078852.1 DNA-binding response regulator Virulence factor MUTATION: virG mutant is avirulent in hamsters [Ref6614:Nierman et al., 2004]. COG0745TK, under T: Signal transduction mechanisms; K: Transcription 15377793 1976 virG from Burkholderia mallei SAVP1 Burkholderia mallei SAVP1 4677485 121597699 BMASAVP1_0602 YP_990210.1 DNA-binding response regulator Virulence factor MUTATION: virG mutant is avirulent in hamsters [Ref6614:Nierman et al., 2004]. COG0745TK, under T: Signal transduction mechanisms; K: Transcription 15377793 2020 BMAA0739 Burkholderia mallei ATCC 23344 3086085 53717365 BMAA0739 CP000011 YP_105468 hypothetical protein Virulence factor MUTATION: BMAA0739 (tssE) is attenuated in hamsters [Ref6638:Schell et al., 2007]. COG3520S, under S: Function unknown 17555434 2021 BMAA0743 Burkholderia mallei ATCC 23344 3086187 77358966 BMAA0743 CP000011 YP_338392 hypothetical protein Virulence factor MUTATION: BMAA0743 (tssB) mutant is attenuated in hamsters [Ref6638:Schell et al., 2007]. COG3517S, under S: Function unknown 17555434 2022 virG from Burkholderia mallei ATCC 23344 Burkholderia mallei ATCC 23344 3086213 53717367 BMAA0746 YP_105470.1 DNA-binding response regulator Virulence factor MUTATION: virG mutant is avirulent in hamsters [Ref6614:Nierman et al., 2004]. COG0745TK, under T: Signal transduction mechanisms; K: Transcription 15377793 2023 BMAA0742 Burkholderia mallei ATCC 23344 3086253 77358963 BMAA0742 CP000011 YP_338391 hypothetical protein Virulence factor MUTATION: BMAA0742 (hcp1) mutant is attenuated in hamsters [Ref6638:Schell et al., 2007]. COG3157S, under S: Function unknown 17555434 2024 BMAA0649 Burkholderia mallei ATCC 23344 3086328 53717435 BMAA0649 CP000011 YP_105401 hemagluttinin motif-containing protein Virulence factor MUTATION: boaA (BMAA0649) mutant has reduced adherence to human epithelial cell lines, specifically HEp2 (laryngeal cells) and A549 (type II pneumocytes), as well as to cultures of normal human bronchial epithelium (NHBE) compared to the wild type [Ref6639:Balder et al., 2010]. 20920184 2025 BMAA0740 Burkholderia mallei ATCC 23344 3086415 77358961 BMAA0740 CP000011 YP_338389 hypothetical protein Virulence factor MUTATION: BMAA0740 (tssD) mutant is attenuated in hamsters [Ref6638:Schell et al., 2007]. COG3519S, under S: Function unknown 17555434 4884 capsule Burkholderia mallei Virulence factor MUTATION: B. mallei capsule mutants display significant attenuation in the Syrian hamster challenge model and the BALB/c aerosol challenge model [Ref7294:Larsen and Johnson, 2009]. 19585782