Protegen ID	Gene Name	Sequence Strain (Species/Organism)	NCBI Gene ID	NCBI Nucleotide GI	NCBI Protein GI	Locus Tag	Genbank Accession	Protein Accession	Protein Name	Protein Annotation	Molecule Role	Molecule Role Annotation	COG	PMID
852	plc from Clostridium perfringens str. 13	Clostridium perfringens str. 13	988262		18309018	CPE0036		NP_560952.1	phospholipase C		Virulence factor	MUTATION: plc mutant is attenuated in mice [Ref6425:Awad et al., 1995].		7746141
853	pfoA	Clostridium perfringens str. 13	988404		18309145	CPE0163	BA000016	NP_561079	perfringolysin O		Virulence factor	TOXIN: perfringolysin O is a pore forming toxin that kills eukaryotic cells by making holes in the cell membrane by attaching to cholesterol [Ref6426:Rossjohn et al., 1997].		9182756
854	virS from Clostridium perfringens str. 13	Clostridium perfringens str. 13	989810		18310482	CPE1500		NP_562416.1	two-component sensor histidine kinase		Virulence factor	MUTATION: virS mutant is attenuated in mice [Ref6427:Lyristis et al., 1994].	COG2972T, under T: Signal transduction mechanisms	8052128
1908	pCPF5603_44	Clostridium perfringens	3897013		86559647	pCPF5603_44	AB236337	YP_473467	beta-2 toxin		Virulence factor	MUTATION: beta toxin null mutants are attenuated in rabbit ileal loop model of disease [Ref6597:Sayeed et al., 2008].		18078439
1921	plc from Clostridium perfringens ATCC 13124	Clostridium perfringens ATCC 13124	4201274		110800852	CPF_0042		YP_694509.1	phospholipase C		Virulence factor	MUTATION: plc mutant is attenuated in mice [Ref6425:Awad et al., 1995].		7746141
1922	virS from Clostridium perfringens ATCC 13124 	Clostridium perfringens ATCC 13124 	4203452		110801372	CPF_1751		YP_696187.1	sensor histidine kinase VirS		Virulence factor	MUTATION: virS mutant is attenuated in mice [Ref6427:Lyristis et al., 1994].	COG2972T, under T: Signal transduction mechanisms	8052128
1923	cpe	Clostridium perfringens SM101	4204801		110801889	CPR_0381	CP000312	YP_697710	enterotoxin Cpe		Virulence factor	MUTATION: cpe knockout mutant is avirulent in rabbit ileal loop model [Ref6609:Sarker et al., 1999].		10476029
1924	virS from Clostridium perfringens SM101	Clostridium perfringens SM101	4204855		110802912	CPR_1481		YP_698800.1	sensor histidine kinase VirS		Virulence factor	MUTATION: virS mutant is attenuated in mice [Ref6427:Lyristis et al., 1994].	COG2972T, under T: Signal transduction mechanisms	8052128
1925	plc from Clostridium perfringens SM101	Clostridium perfringens SM101	4205371		110802823	CPR_0041		YP_697384.1	phospholipase C		Virulence factor	MUTATION: plc mutant is attenuated in mice [Ref6425:Awad et al., 1995].		7746141
3367	pCP8533etx_p28	Clostridium perfringens	7003474		209947607	pCP8533etx_p28	M80837	YP_002291114	epsilon toxin		Virulence factor	TOXIN: epsilon-toxin interacts with vascular endothelial cells and increases the vessel wall permeability by direct damage of the endothelium [Ref6801:Adamson et al., 2005].		16041001