Protegen ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Protein Annotation Molecule Role Molecule Role Annotation COG PMID 4892 aroA Bordetella bronchiseptica RB50 2659145 33602442 BB3469 BX640447 NP_890002 3-phosphoshikimate 1-carboxyvinyltransferase Virulence factor MUTATION: Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice [Ref7323:Stevenson and Roberts, 2002]. 12009288 4946 bscN Bordetella bronchiseptica RB50 2662485 33600613 BB1628 BX640441 NP_888173 type III secretion system ATPase Virulence factor MUTATION: A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated in mice [Ref7366:Mann et al., 2007]. 17452472 4947 cyaA Bordetella bronchiseptica RB50 2661688 33599313 BB0324 BX640437 NP_886873 bifunctional hemolysin-adenylate cyclase precursor Virulence factor MUTATION: A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated in mice [Ref7366:Mann et al., 2007]. 17452472 4948 dnt Bordetella bronchiseptica RB50 2661538 33602952 BB3978 BX640449 NP_890512 dermonecrotic toxin Virulence factor MUTATION: A dnt mutant in Bordetella Bronchiseptica was attenuated in guinea pigs [Ref7367:Nagano et al., 1988]. 3182989 4949 trpE Paenibacillus sp. Y412MC10 8515760 261405430 GYMC10_1581 CP001793 YP_003241671 UBA/THIF-type NAD/FAD-binding protein Virulence factor MUTATION: A trpE mutant, in combination with an aroA mutation, is attenuated in mice [Ref7368:McArthur et al., 2003]. 12694904