Protegen ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Protein Annotation Molecule Role Molecule Role Annotation COG PMID 2562 boNT/A1 from Clostridium botulinum A str. ATCC 19397 Clostridium botulinum A str. ATCC 19397 5397793 153931567 CLB_0848 YP_001383190.1 botulinum neurotoxin type A1, BoNT/A1 Virulence factor MUTATION: inserting a group II intron into the botulinum neurotoxin type A gene (bont/A) rendered mutant clones nontoxigenic [Ref6699:Bradshaw et al., 2010] 19933346 2563 boNT/A1 from Clostridium botulinum A str. Hall Clostridium botulinum A str. Hall 5398487 153936924 CLC_0862 YP_001386738.1 botulinum neurotoxin type A1, BoNT/A1 Virulence factor MUTATION: a BoNT/A mutant was rendered nontoxigenic [Ref6699:Bradshaw et al., 2010] 19933346 2564 boNT/B Clostridium botulinum B1 str. Okra 6030102 169834607 CLD_A0068 AB232927 YP_001693307 botulinum neurotoxin type B Virulence factor MUTATION: BoNT/B toxoid without non-toxic components, which are generally associated with the toxin was used attenuated and used as a vaccine candidate [Ref6700:Yang et al., 2004] 15225558 2565 boNT/A3 Clostridium botulinum A3 str. Loch Maree 6030483 169835008 CLK_A0076 CP000963 YP_001715703 botulinum neurotoxin type A3 Virulence factor TOXIN: BoNT/A3 is a neurotoxin with prolonged effects [Ref6701:Smith et al., 2007] 18060065 2566 boNT/E3 Clostridium botulinum E3 str. Alaska E43 6319260 188590132 CLH_1110 CP001078 YP_001920504 botulinum neurotoxin, type E3, BoNT/E3 Virulence factor MUTATION: BoNT/E mutants were nontoxigenic as opposed to the toxigenic wild type strain [Ref6702:Hawirko et al., 1973] 4633199 3676 pC2C203U28_p056 Clostridium botulinum 7636529 225166789 pC2C203U28_p056 AP010934 YP_002650774 C2 toxin,component I Virulence factor TOXIN: C2 toxin is the prototype of actin-ADP-ribosylating toxins and produces enterotoxic effects in humans [Ref6835:Aktories and Barth, 2004] 16701506 3677 pC2C203U28_p057 Clostridium botulinum 7636534 225166790 pC2C203U28_p057 AB465552 YP_002650775 C2 toxin,component II Virulence factor TOXIN: C2 toxin is the prototype of actin-ADP-ribosylating toxins, and produces enterotoxic effects in humans [Ref6835:Aktories and Barth, 2004] 16701506