Protegen ID	Gene Name	Sequence Strain (Species/Organism)	NCBI Gene ID	NCBI Nucleotide GI	NCBI Protein GI	Locus Tag	Genbank Accession	Protein Accession	Protein Name	Protein Annotation	Molecule Role	Molecule Role Annotation	COG	PMID
4489	orf3a 	SARS coronavirus ZJ0301			74275591				putative transmembrane protein 3a; Orf3a		Virulence factor	MUTATION: or3a deficient strain of SARS-CoV is attenuated in causing death of Vero cells [Ref7026:Anan'eva, 1998].; 		9889773
4490	nsp1	SARS coronavirus ExoN1			270309758				orf1a polyprotein		Virulence factor	MUTATION: nsp1 mutant is attenuated in Vero cells [Ref7027:Wathelet et al., 2007].; 		17715225
5008	E 	Severe acute respiratory syndrome-related coronavirus	1489671		29836499	sars4		NP_828854	protein E		Virulence factor	MUTATION: An E mutant is attenuated in hamsters [Ref7417:Lamirande et al., 2008]. 		18463152
5400	nsp4	Severe acute respiratory syndrome-related coronavirus			34555778				nsp4-pp1a/pp1ab		Virulence factor	Mutation in SARS-CoV nsp4 protein attenuated viral replication in 293T cell. [Ref7765:Sakai Y et al., 2017]		28738245
5401	N nucleocapsid	Severe acute respiratory syndrome-related coronavirus	1489678		29836503	sars9a	AY274119	NP_828858	nucleocapsid protein		Virulence factor	SARS-CoV N nucleocapsid protein suppresses the human immune response by inhibiting Type 1 interferon production. [Ref7766:Hu Y et al., 2017]		28148787 
5403	nsp3